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  • ISSN 1674-8301
  • CN 32-1810/R
Volume 31 Issue 6
Oct.  2017
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Natalia Liapounova, Kamran H. Azar, J. Max Findlay, Jian-Qiang Lu. Vanishing cerebral vasculitis in a patient with Lewy pathology[J]. The Journal of Biomedical Research, 2017, 31(6): 559-562. DOI: 10.7555/JBR.31.20160119
Citation: Natalia Liapounova, Kamran H. Azar, J. Max Findlay, Jian-Qiang Lu. Vanishing cerebral vasculitis in a patient with Lewy pathology[J]. The Journal of Biomedical Research, 2017, 31(6): 559-562. DOI: 10.7555/JBR.31.20160119
shu

Vanishing cerebral vasculitis in a patient with Lewy pathology

  • 1.

    Division of Pediatric Neurology, University of Alberta, Edmonton, Alberta, Canada

  • 2.

    Department of Pathology, The North East Health Services Delivery Area, Fort St. John, British Columbia, Canada

  • 3.

    Division of Neurosurgery, University of Alberta, Edmonton, Alberta, Canada

  • 4.

    Neuropathology Section, Department of Laboratory Medicine and Pathology, University of Alberta, University of Alberta, Edmonton, Alberta, Canada

More Information
  • Received Date: September 19, 2016
    Graphical Abstract
    • Abstract
  • Immune-mediated mechanisms are involved in the pathogenesis of both cerebral vasculitis and Parkinson's disease (PD, brainstem-predominant Lewy pathology), but the presentation of cerebral vasculitis with comorbid Lewy pathology has not yet been reported. Here we present a case of pathologically confirmed vasculitis in a 73-year-old male patient whose postmortem examination revealed Lewy pathology diagnostic of PD. This case study suggests a comorbidity of cerebral vasculitis and Lewy pathology, as well as potential pathogenic interactions between these two disorders with immune-mediated mechanisms.
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