4.6

CiteScore

2.2

Impact Factor
  • ISSN 1674-8301
  • CN 32-1810/R
Volume 26 Issue 6
Oct.  2012
Turn off MathJax
Article Contents
Abstract
Related Articles
Jiaxin Ye, Ping Ni, Lina Kang, Biao Xu. Apelin and vascular endothelial growth factor are associated with mobilization of endothelial progenitor cells after acute myocardial infarction[J]. The Journal of Biomedical Research, 2012, 26(6): 400-409. DOI: 10.7555/JBR.26.20120052
Citation: Jiaxin Ye, Ping Ni, Lina Kang, Biao Xu. Apelin and vascular endothelial growth factor are associated with mobilization of endothelial progenitor cells after acute myocardial infarction[J]. The Journal of Biomedical Research, 2012, 26(6): 400-409. DOI: 10.7555/JBR.26.20120052
shu

Apelin and vascular endothelial growth factor are associated with mobilization of endothelial progenitor cells after acute myocardial infarction

  • 1.

    Department of Cardiology, Drum Tower Clinical College Affiliated with Nanjing Medical University, Nanjing, Jiangsu 210008, China

  • 2.

    Department of Cardiology, Drum Tower Hospital (L.N.K.), Nanjing, Jiangsu 210008, China

Funds: 

This work was supported by the program (No. CX10B_421Z to Jiaxin Ye) for Postgraduate Research Innovation in Universities of Jiangsu Province

the grants (No. 81070195) and (No. 81000055) from Chinese National Science Fund of China (all to Biao Xu), and grant (No. KF200938 to Lina Kang) from Jiangsu Province.

More Information
  • Received Date: May 14, 2012
    Graphical Abstract
    • Abstract
  • This study was designed to determine the levels of early endothelial progenitor cells (EPCs), apelin, vascu-lar endothelial growth factor (VEGF) and stromal cell-derived growth factor-1 (SDF-1) after acute myocardial infarction (AMI), and to investigate the relationships between these cytokines and early EPCs. Early EPCs, de-fined as CD133+, KDR+, and CD34+ cells, were quantified by flow cytometry. The levels of early EPCs and those cytokines in AMI patients were significantly different from those with coronary artery disease or controls (P < 0.05). Plasma apelin levels were inversely correlated with Gensini score and early EPCs (both P < 0.01). Early EPCs, VEGF and SDF-1 showed different patterns of changes in AMI patients during the first 24 h. The trend in the change of early EPCs was proportionally correlated with that of VEGF (P < 0.05). AMI patients exhibited in-creased early EPCs with remarkably decreased apelin levels and enhanced VEGF levels.
    • FullText(HTML)
    • References (0)
    • Related Articles

  • Related Articles

    [1]Ziyu Zhao, Yi Zhou, Jinxing Guan, Yan Yan, Jing Zhao, Zhihang Peng, Feng Chen, Yang Zhao, Fang Shao. The relationship between compartment models and their stochastic counterparts: A comparative study with examples of the COVID-19 epidemic modeling[J]. The Journal of Biomedical Research, 2024, 38(2): 175-188. DOI: 10.7555/JBR.37.20230137
    [2]Gurumurthy Channabasavaiah B., Saunders Thomas L., Ohtsuka Masato. Designing and generating a mouse model: frequently asked questions[J]. The Journal of Biomedical Research, 2021, 35(2): 76-90. DOI: 10.7555/JBR.35.20200197
    [3]Quintero-Rincón Antonio, D'Giano Carlos, Batatia Hadj. A quadratic linear-parabolic model-based EEG classification to detect epileptic seizures[J]. The Journal of Biomedical Research, 2020, 34(3): 205-212. DOI: 10.7555/JBR.33.20190012
    [4]Wang Le Yi, McKelvey George M., Wang Hong. Multi-outcome predictive modelling of anesthesia patients[J]. The Journal of Biomedical Research, 2019, 33(6): 430-434. DOI: 10.7555/JBR.33.20180088
    [5]Maglione Michele, Salvador Enrico, Ruaro Maria E., Melato Mauro, Tromba Giuliana, Angerame Daniele, Bevilacqua Lorenzo. Bone regeneration with adipose derived stem cells in a rabbit model[J]. The Journal of Biomedical Research, 2019, 33(1): 38-45. DOI: 10.7555/JBR.32.20160066
    [6]Robert Scott Kiss, Allan Sniderman. Shunts, channels and lipoprotein endosomal traffic: a new model of cholesterol homeostasis in the hepatocyte[J]. The Journal of Biomedical Research, 2017, 31(2): 95-107. DOI: 10.7555/JBR.31.20160139
    [7]Mingming Gao, Guo Xin, Xu Qiu, Yuhui Wang, George Liu. Establishment of a rat model with diet-induced coronary atherosclerosis[J]. The Journal of Biomedical Research, 2017, 31(1): 47-55. DOI: 10.7555/JBR.31.20160020
    [8]Jiawei Liao, Wei Huang, George Liu. Animal models of coronary heart disease[J]. The Journal of Biomedical Research, 2017, 31(1): 3-10. DOI: 10.7555/JBR.30.20150051
    [9]Zengdi Zhang, Sanen Li, Steven Y Cheng. The miR-183~96~182 cluster promotes tumorigenesis in a mouse model of medulloblastoma[J]. The Journal of Biomedical Research, 2013, 27(6): 486-494. DOI: 10.7555/JBR.27.20130010
    [10]Keh-Dong Shiang, Fouad Kandeel. A computational model of the human glucose-insulin regulatory system[J]. The Journal of Biomedical Research, 2010, 24(5): 347-364. DOI: 10.1016/S1674-8301(10)60048-6

  • Cited by

    Periodical cited type(5)

    1. Langyan S, Bhardwaj R, Kumari J, et al. Nutritional Diversity in Native Germplasm of Maize Collected From Three Different Fragile Ecosystems of India. Front Nutr, 2022, 9: 812599. DOI:10.3389/fnut.2022.812599
    2. Juvinao-Quintero DL, Cardenas A, Perron P, et al. Associations between an integrated component of maternal glycemic regulation in pregnancy and cord blood DNA methylation. Epigenomics, 2021, 13(18): 1459-1472. DOI:10.2217/epi-2021-0220
    3. Zhang J, Wu X. Predict Health Care Accessibility for Texas Medicaid Gap. Healthcare (Basel), 2021, 9(9): 1214. DOI:10.3390/healthcare9091214
    4. Ayati M, Koyutürk M. PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases. PLoS Comput Biol, 2016, 12(11): e1005195. DOI:10.1371/journal.pcbi.1005195
    5. Zhang Q, Zhao Y, Zhang R, et al. A Comparative Study of Five Association Tests Based on CpG Set for Epigenome-Wide Association Studies. PLoS One, 2016, 11(6): e0156895. DOI:10.1371/journal.pone.0156895

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML

    Article Metrics

    Article has an altmetric score of 1
    Article has an altmetric score of 1
    Article views (4831) PDF downloads (1379) Cited by(5)
    Related

    ©2023 by the Editorial Department of the Journals of Nanjing Medical University. All rights reserved.   苏ICP备05071376号-5

    Supported by: Beijing Renhe Information Technology Co., Ltd. E-mail: info@rhhz.net  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return