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  • ISSN 1674-8301
  • CN 32-1810/R
Volume 28 Issue 4
Jun.  2014
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Abstract
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Fang Zhou, Haifeng Zhang, Wenming Yao, Hongbin Mei, Dongjie Xu, Yanhui Sheng, Rong Yang, Xiangqing Kong, Liansheng Wang, Jiangang Zou, Zhijian Yang, Xinli Li. Relationship between brachial-ankle pulse wave velocity and metabolic syndrome components in a Chinese population[J]. The Journal of Biomedical Research, 2014, 28(4): 262-268. DOI: 10.7555/JBR.28.20130160
Citation: Fang Zhou, Haifeng Zhang, Wenming Yao, Hongbin Mei, Dongjie Xu, Yanhui Sheng, Rong Yang, Xiangqing Kong, Liansheng Wang, Jiangang Zou, Zhijian Yang, Xinli Li. Relationship between brachial-ankle pulse wave velocity and metabolic syndrome components in a Chinese population[J]. The Journal of Biomedical Research, 2014, 28(4): 262-268. DOI: 10.7555/JBR.28.20130160
shu

Relationship between brachial-ankle pulse wave velocity and metabolic syndrome components in a Chinese population

  • 1.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

  • 2.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210030, China

  • 3.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210031, China

  • 4.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210032, China

  • 5.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210033, China

  • 6.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210034, China

  • 7.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210035, China

  • 8.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210036, China

  • 9.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210037, China

  • 10.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210038, China

  • 11.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210039, China

  • 12.

    Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210040, China

Funds: 

This study was support by grants from the National Key Technologies R&D Program of China during the 11th Five-Year Plan Period (2007BAI07A10), the Jiangsu Province Science and Technology Support Program (BE2009613), the 9th Six Talents Peak Project of Jiangsu Province (WS-022), and the Qing Lan Project.

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  • Received Date: October 10, 2013
    Graphical Abstract
    • Abstract
  • The purpose of this study was to assess the relationship between arterial stiffness, as measured by brachial-ankle pulse wave velocity (baPWV), and the presence of the metabolic syndrome (MS) in a Chinese population. A total of 4,445 subjects were enrolled. The prevalence of MS in our study population was 21.7%, 17.2% and 25.6% for the general population, males and females, respectively. With adjustments for age, gender, cigarette smoking, heart rate, total cholesterol, low-density lipoprotein (LDL) cholesterol, and the use of anti-hypertensive drug, the stepwise regression analysis showed that baPWV had a significant relationship with components of MS, including systolic blood pressure (P , 0.001), diastolic blood pressure (P , 0.001), glucose (P , 0.001), highdensity lipoprotein (HDL) cholesterol (P 5 0.04), and triglycerides (P , 0.001), but no relationship with waist circumference (P 5 0.25). With an increase in the number of the MS components, baPWV increased significantly both in women and men. This study indicated that the MS is indeed a risk factor for arterial stiffness. Monitoring of baPWV in patients with MS may help in identifying persons at high risk for cardiovascular disease.
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