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  • ISSN 1674-8301
  • CN 32-1810/R
Volume 28 Issue 5
Aug.  2014
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Abstract
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Rajiv Shrestha, Jing Xu, Dujiang Xie, Zhizhong Liu, Tian Xu, Fei Ye, Shiqing Din, Xuesong Qian, Song Yang, Yueqiang Liu, Feng Li, Aiping Zhang, Shaoliang Chen. Comparison of clinical outcomes of Chinese men and women after coronary stenting for coronary artery disease: a multi-center retrospective analysis of 4,334 patients[J]. The Journal of Biomedical Research, 2014, 28(5): 368-375. DOI: 10.7555/JBR.28.20120127
Citation: Rajiv Shrestha, Jing Xu, Dujiang Xie, Zhizhong Liu, Tian Xu, Fei Ye, Shiqing Din, Xuesong Qian, Song Yang, Yueqiang Liu, Feng Li, Aiping Zhang, Shaoliang Chen. Comparison of clinical outcomes of Chinese men and women after coronary stenting for coronary artery disease: a multi-center retrospective analysis of 4,334 patients[J]. The Journal of Biomedical Research, 2014, 28(5): 368-375. DOI: 10.7555/JBR.28.20120127
shu

Comparison of clinical outcomes of Chinese men and women after coronary stenting for coronary artery disease: a multi-center retrospective analysis of 4,334 patients

  • 1.

    Department of Cardiology, Nanjing Medical University, Nanjing, Jiangsu 210029, China

  • 2.

    Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China

  • 3.

    Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210007, China

  • 4.

    Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210008, China

  • 5.

    Department of Cardiology, Huainan Xinhua Hospital, Huainan, Anhui 232038, China

  • 6.

    Department of Cardiology, Zhangjiagang People9 s Hospital, Zhangjiagang, Jiangsu 215600, China

  • 7.

    Department of Cardiology, Yixin People9 s Hospital, Yixin, Jiangsu 214200, China

  • 8.

    Department of Cardiology, Jintan People9 s Hospital, Jintan, Jiangsu 213200, China

  • 9.

    Department of Cardiology, Huainan Oriental General Hospital, Huainan, Anhui 235056, China

  • 10.

    Department of Cardiology, Huainan People9 s Hospital, Huainan, Anhui 340016, China

Funds: 

This study was supported by the Nanjing Municipal Health Outstanding Project (2000NJMHOP-120).

More Information
  • Received Date: December 23, 2012
  • Revised Date: May 15, 2013
    Graphical Abstract
    • Abstract
  • The outcome differences between Chinese male and female patients within one-year follow-up after percutaneous coronary intervention (PCI) with stent remain unclear. The present study was aimed to compare clinical outcomes in such two populations. From May 1999 to December 2009, 4,334 patients with acute myocardial infarction (MI), unstable angina, stable angina, or silent ischemia, who underwent PCI, were registered at our centers. Among these, 3,089 were men and 1,245 were women. We compared these groups with respect to the primary outcomes of MI and secondary outcomes including a composite of major adverse cardiac events (MACE) including cardiac death, MI, target lesion revascularization, target vessel revascularization (TVR), stent thrombosis (ST), definite ST and probable ST at one-year follow-up. Chinese male patients had a higher MACE rate (13% vs. 10.7%, P = 0.039), mainly led by TVR (9.09% vs. 6.98%, P50.024) at one year, which was significantly different than female patients. Chinese male and female patients showed a significant difference on MACEs. However, there was no significant difference with respect to MI between these groups.
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