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  • ISSN 1674-8301
  • CN 32-1810/R
Volume 25 Issue 4
Jun.  2011
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Abstract
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Xiuxiu Hu, Jingde Dong, Xiaoshan Wang, Ting Wu, Lu Yang, Xiaopeng Lu. Localization of epileptic foci in Children with childhood absence epilepsy by magnetoencephalography combined with synthetic aperture magnetometry☆[J]. The Journal of Biomedical Research, 2011, 25(4): 259-265. DOI: 10.1016/S1674-8301(11)60035-3
Citation: Xiuxiu Hu, Jingde Dong, Xiaoshan Wang, Ting Wu, Lu Yang, Xiaopeng Lu. Localization of epileptic foci in Children with childhood absence epilepsy by magnetoencephalography combined with synthetic aperture magnetometry☆[J]. The Journal of Biomedical Research, 2011, 25(4): 259-265. DOI: 10.1016/S1674-8301(11)60035-3
shu

Localization of epileptic foci in Children with childhood absence epilepsy by magnetoencephalography combined with synthetic aperture magnetometry☆

  • 1.

    Department of Geriatric Neurology, Nanjing Brain Hospital, Nanjing, Jiangsu 210029, China

  • 2.

    Magnetoencephalography Center, Nanjing Brain Hospital, Nanjing, Jiangsu 210029, China

  • 3.

    Department of Neurology, Nanjing Children’s Hospital, Nanjing, Jiangsu 210029, China

Funds: 

Nanjing Medical Technology Develop-ment Grant (No. ZKM05033)

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  • Received Date: March 10, 2011
    Graphical Abstract
    • Abstract
  • This present study was aimed to investigate the localizable diagnostic value of magnetoencephalography (MEG) combined with synthetic aperture magnetometry (SAM) in childhood absence epilepsy (CAE). Thirteen CAE pa-tients underwent MEG detection at resting state and after hyperventilation, and then the epileptic foci were located by SAM. In the thirteen CAE patients, epileptic foci were found in five cases (38.5%) , and they were all located in the bilateral frontal lobe, suggesting that the frontal lobe in some CAE patients may serve as the epileptic foci. Our findings indicate that MEG combined with SAM could be of diagnostic value in localizing the epileptic foci in certain CAE patients.
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