Natalia Liapounova, Kamran H. Azar, J. Max Findlay, Jian-Qiang Lu. Vanishing cerebral vasculitis in a patient with Lewy pathology[J]. The Journal of Biomedical Research, 2017, 31(6): 559-562. DOI: 10.7555/JBR.31.20160119
Citation:
Natalia Liapounova, Kamran H. Azar, J. Max Findlay, Jian-Qiang Lu. Vanishing cerebral vasculitis in a patient with Lewy pathology[J]. The Journal of Biomedical Research, 2017, 31(6): 559-562. DOI: 10.7555/JBR.31.20160119
Natalia Liapounova, Kamran H. Azar, J. Max Findlay, Jian-Qiang Lu. Vanishing cerebral vasculitis in a patient with Lewy pathology[J]. The Journal of Biomedical Research, 2017, 31(6): 559-562. DOI: 10.7555/JBR.31.20160119
Citation:
Natalia Liapounova, Kamran H. Azar, J. Max Findlay, Jian-Qiang Lu. Vanishing cerebral vasculitis in a patient with Lewy pathology[J]. The Journal of Biomedical Research, 2017, 31(6): 559-562. DOI: 10.7555/JBR.31.20160119
Immune-mediated mechanisms are involved in the pathogenesis of both cerebral vasculitis and Parkinson's disease
(PD, brainstem-predominant Lewy pathology), but the presentation of cerebral vasculitis with comorbid Lewy
pathology has not yet been reported. Here we present a case of pathologically confirmed vasculitis in a 73-year-old
male patient whose postmortem examination revealed Lewy pathology diagnostic of PD. This case study suggests a
comorbidity of cerebral vasculitis and Lewy pathology, as well as potential pathogenic interactions between these two
disorders with immune-mediated mechanisms.
Cheng A, Wang YF, Shinoda Y, et al. Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress. Acta Pharmacol Sin, 2022, 43(3): 552-562.
DOI:10.1038/s41401-021-00675-8