• ISSN 1674-8301
  • CN 32-1810/R
Volume 27 Issue 4
Jul.  2013
Turn off MathJax
Article Contents
Li Zhang, Jingde Dong, Weiguo Liu, Yingdong Zhang. Subjective poor sleep quality in Chinese patients with Parkinson's disease without dementia[J]. The Journal of Biomedical Research, 2013, 27(4): 291-295. doi: 10.7555/JBR.27.20120143
Citation: Li Zhang, Jingde Dong, Weiguo Liu, Yingdong Zhang. Subjective poor sleep quality in Chinese patients with Parkinson's disease without dementia[J]. The Journal of Biomedical Research, 2013, 27(4): 291-295. doi: 10.7555/JBR.27.20120143

Subjective poor sleep quality in Chinese patients with Parkinson's disease without dementia

doi: 10.7555/JBR.27.20120143
Funds:

The project was supported by Medical Science and Technology Development Foundation, Nanjing Department of Health (No. ZKX12037 ) and the Opening Project of Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University (No. SJ11KF03).

  • Received: 2012-12-22
  • Issue Date: 2013-07-28
  • Parkinson's disease (PD) is a common progressive neurological disorder and is composed of motor and non-motor symptoms. Sleep disturbances are frequent problems for patients with PD. The relationship between sleep disturbances with Hoehn and Yahr (H&Y) staging have been demonstrated. However, the relationship between sleep disorders and H&Y is still unclear in patients with PD without dementia in Chinese PD patients. In this study, we interviewed 487 non-demented PD patients of Chinese Han descents by H&Y classification. We found that night sleep quality was significantly associated with the severity of PD (P = 0.008). Panic disorder severity scale (PDSS) total scores were correlated with PD non-motor symptoms scale (PDNMS) scores (r = -0.528, P < 0.001), the Hamilton depression scale (HAMD) scores (r = -0.545, P < 0.001) and the Hamilton anxiety scale (HAMA) scores (r = -0.498, P < 0.001). Our results indicated that sleep quality deteriorated with the advancing of PD in Chinese non-demented patients with PD. Depression and anxiety may partly explain sleep disturbances in non-demented patients with PD.

     

  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (3569) PDF downloads(864) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return