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  • ISSN 1674-8301
  • CN 32-1810/R
Volume 30 Issue 5
Aug.  2016
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Jun Han, Chuanbing Shi, Xiaogang Dong, Jie Wang, Hao Wen, Baolin Wang, Zhenyu He. Laparoscopic abdomino-perineal resection for patients with anorectal malignant melanoma: a report of 4 cases[J]. The Journal of Biomedical Research, 2016, 30(5): 436-440. DOI: 10.7555/JBR.27.20120099
Citation: Jun Han, Chuanbing Shi, Xiaogang Dong, Jie Wang, Hao Wen, Baolin Wang, Zhenyu He. Laparoscopic abdomino-perineal resection for patients with anorectal malignant melanoma: a report of 4 cases[J]. The Journal of Biomedical Research, 2016, 30(5): 436-440. DOI: 10.7555/JBR.27.20120099
shu

Laparoscopic abdomino-perineal resection for patients with anorectal malignant melanoma: a report of 4 cases

  • 1.

    Department of General Surgery, the Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210011, China

  • 2.

    Department of Pathology, the Second Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210011, China

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  • Received Date: September 19, 2012
  • Revised Date: October 05, 2012
    Graphical Abstract
    • Abstract
  • Anorectal malignant melanoma is a very rare but lethal disease. Patients with anorectal malignant melanoma commonly complain for changes in bowel habits and rectal bleeding. Therefore, anorectal malignant melanoma is often misdiagnosed as hemorrhoids, polyp or rectal cancer. Surgery is the mainstay of treatment for patients with anorectal malignant melanoma. However, whether abdominoperineal resection or wide local excision is the most appropriate surgical approach is still a controversial issue. Recently, with the great development of laparoscopic techniques, more and more operations can be performed by laparoscopic techniques. However, laparoscopic abdom-inoperineal resection for management of anorectal malignant melanoma has been rarely reported. In this study, we reported 4 patients with anorectal malignant melanoma underwent laparoscopic abdominoperineal resection. The outcomes of these patients were relatively good during a long time follow-up. Meanwhile, we reviewed the relevant studies with particular focus surgical treatment.
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    1. Paolino G, Podo Brunetti A, De Rosa C, et al. Anorectal melanoma: systematic review of the current literature of an aggressive type of melanoma. Melanoma Res, 2024, 34(6): 487-496. DOI:10.1097/CMR.0000000000001003
    2. Illa SK, Mumtaz S, Nath S, et al. Characterization of runs of Homozygosity revealed genomic inbreeding and patterns of selection in indigenous sahiwal cattle. J Appl Genet, 2024, 65(1): 167-180. DOI:10.1007/s13353-023-00816-1
    3. Ugonabo O, Mohamed M, Ezeh E, et al. A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male. J Med Cases, 2022, 13(8): 369-373. DOI:10.14740/jmc3929
    4. Si M, Cao X. Considering Computational Mathematics IGHG3 as Malignant Melanoma Is Associated with Immune Infiltration of Malignant Melanoma. Biomed Res Int, 2022, 2022: 4168937. DOI:10.1155/2022/4168937
    5. Nonaka K, Kudou K, Sasaki S, et al. Primary anorectal malignant melanoma with laparoscopic abdominoperineal resection: a case study and review of the relevant literature. Int Cancer Conf J, 2020, 9(3): 116-122. DOI:10.1007/s13691-020-00401-x
    6. Heo JR, Hwang KA, Kim SU, et al. A Potential Therapy Using Engineered Stem Cells Prevented Malignant Melanoma in Cellular and Xenograft Mouse Models. Cancer Res Treat, 2019, 51(2): 797-811. DOI:10.4143/crt.2018.364

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