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Bidirectional Mendelian randomization and mediation analysis of million-scale data reveal causal relationships between thyroid-related phenotypes, smoking, and lung cancer .

Figures of the Article

The workflow diagram of the current study.
Scatter plots showing the associations between thyroid function-related phenotypes and lung cancer in the overall population.
The causal graph of smoking phenotypes, thyroid-related phenotypes, and lung cancer.
Forest plots for the results of stratified MR analysis.
Mediation analysis for the association between thyroid-related phenotypes, smoking phenotypes, and lung cancer risk.

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