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Volume 36 Issue 5
Sep.  2022
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Haoran Jia, Tianwu Xie. Tracers progress for positron emission tomography imaging of glial-related disease[J]. The Journal of Biomedical Research, 2022, 36(5): 321-335. doi: 10.7555/JBR.36.20220017
Citation: Haoran Jia, Tianwu Xie. Tracers progress for positron emission tomography imaging of glial-related disease[J]. The Journal of Biomedical Research, 2022, 36(5): 321-335. doi: 10.7555/JBR.36.20220017

Tracers progress for positron emission tomography imaging of glial-related disease

doi: 10.7555/JBR.36.20220017
Funds:  This work was supported by the Key Laboratory of Biomedical Engineering of Hainan Province under Opening Foundation 2022001.
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  • Corresponding author: Tianwu Xie, Institute of Radiation Medicine, Fudan University, 2094 Xietu Road, Shanghai 200032, China. Tel: +86-21-64048363, E-mail: tianwuxie@fudan.edu.cn
  • Received: 2022-01-23
  • Revised: 2022-04-23
  • Accepted: 2022-05-24
  • Published: 2022-06-28
  • Issue Date: 2022-09-28
  • Glial cells play an essential part in the neuron system. They can not only serve as structural blocks in the human brain but also participate in many biological processes. Extensive studies have shown that astrocytes and microglia play an important role in neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, as well as glioma, epilepsy, ischemic stroke, and infections. Positron emission tomography is a functional imaging technique providing molecular-level information before anatomic changes are visible and has been widely used in many above-mentioned diseases. In this review, we focus on the positron emission tomography tracers used in pathologies related to glial cells, such as glioma, Alzheimer's disease, and neuroinflammation.


  • CLC number: R741.04; R817.4, Document code: A
    The authors reported no conflict of interests.
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